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Journal of Environmental Biology

pISSN: 0254-8704 ; eISSN: 2394-0379 ; CODEN: JEBIDP
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    Abstract - Issue Nov 2008, 29 (6)                                     Back


Interactions between marine facultative epiphyte Chlamydomonas sp

Assessment of teratogenecity and embryotoxicity of sludge from textile industries at Pali (India) in Swiss albino mice exposed during organogenetic period

 

Himani I. Soni*, P.P.? Bakre and? P. Bhatnagar

Environmental Toxicology Laboratory, Department of Zoology, University of Rajasthan, Jaipur - 302 004, India

(Received: July 11, 2006; Revised received: February 20, 2007 ; Re-revised received: March 10, 2007 ; Accepted: March 17, 2007)

Abstract: The present investigation was carried out to assess the teratological effects of in-utero exposure of sludge leachate from textile and dyeing industries located in Pali, Rajasthan. Sludge was collected at the combined effluent treatment plant (CETP). Two groups of 10 pregnant Swiss albino mice each, were given sludge leachate of 1/10 and 1/100 dilutions with water ad libitum from 6th day to 15th day of gestation covering the critical period of organogenesis. Cesarean sections were performed on day 18 of gestation and all foetuses were examined for reproductive and teratological tests. Sludge induced maternal toxicity was evidenced by significant increase in leachate consumption, reduction in body weight gain and reduction in fur of the body. Developmental toxicity was evidenced by a significant decrease in foetal weight per litter, increase in the number of resorptions and an increase in total number of foetuses showing bone retardation and skeletal variations (specially of skull, sternebrae and vertebrae). The leachate of the sludge that is being dumped in the open areas of the town Pali seems to elicit teratogenic as well as embryotoxic potential as indicated by the findings of the present investigation.

Key words:?? Teratology, Sludge, Foetus, Embryotoxicity

PDF of full length paper is available with author (*inderpalsoni@gmail.com)

 

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